Prepare the Filling
In a large mixing bowl, combine the shredded chicken, softened cream cheese, sour cream, 1/2 cup of shredded cheese, green chilies, garlic powder, onion powder, cumin, salt, and pepper. Mix until well combined and creamy.
Assemble the Enchiladas
Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch baking dish. Lay a tortilla flat, place a generous scoop of the chicken mixture down the center, and roll it up tightly. Place the rolled tortilla seam-side down in the baking dish. Repeat with the remaining tortillas and filling.
Add the Sauce
Pour the enchilada sauce evenly over the rolled tortillas, making sure they’re well covered. Sprinkle the remaining shredded cheese on top.
Bake the Enchiladas
Cover the baking dish with aluminum foil and bake for 20 minutes. Remove the foil and bake for an additional 10 minutes, or until the cheese is melted and bubbly.
Garnish and Serve
Remove from the oven and let the enchiladas rest for 5 minutes. Garnish with chopped cilantro or green onions, if desired. Serve hot with your favorite toppings.